Differential Diagnosis in Surgical Pathology: Expert Consult by Paolo Gattuso MD, Vijaya B. Reddy MD, Odile David MD, Daniel

By Paolo Gattuso MD, Vijaya B. Reddy MD, Odile David MD, Daniel J. Spitz MD, Meryl H. Haber MD

Differential analysis in Surgical Pathology, second version, by means of Paolo Gattuso, MD, Vijaya B. Reddy, MD, Odile David, MD, and Daniel J. Spitz, MD, is skillfully designed that will help you with a bit of luck signal out your most complicated and demanding instances. protecting a whole variety of tumors and tumor-like stipulations in all organ platforms, it offers a hassle-free highway map to the most standards you need to ponder so one can differentiate among various power diagnoses that every one have a really related visual appeal. Over 1,350 new full-color macro- and microphotographs supply a practical foundation for comparability to what you notice less than the microscope. quickly checklists disguise all diagnostic chances to ensure not anything falls in the course of the cracks. Full-text on-line entry at expertconsult.com enables you to reference the booklet from any laptop and obtain all of its images.A concise, bulleted textual layout enables speedy retrieval of crucial facts.A constant method of analysis and interpretation expedites reference.Coverage of all suitable ancillary diagnostic suggestions addresses all the investigative contexts had to formulate a correct diagnosis.Expert "pearls" supply sensible pointers on what diagnostic standards to think about or exclude.A accomplished, but achievable dimension makes it possible for quickly consultation.Online entry at expertconsult.com enables you to quick seek advice the ebook from any desktop and obtain all of its images.Over 1,350 new full-color macro- and microphotographs supply a practical foundation for comparability to what you notice below the microscope. Immunohistochemical and molecular concepts all through make it easier to evaluate all the most recent diagnostic concerns in a single place.Expanded assurance of non-neoplastic entities assists you in spotting benign lesions which can mimic the looks and features of malignant ones.Extensive updates comprise the most recent type schemes and appropriate diagnostic strategies. A brand-new, color-coded structure highlights key issues extra basically and is helping you switch to the sections you wish extra speedily.Your buy entitles you to entry the website till the subsequent variation is released, or until eventually the present variation is not any longer provided on the market by means of Elsevier, whichever happens first. Elsevier reserves the correct to supply an appropriate alternative product (such as a downloadable or CD-ROM-based digital model) may still entry to the website be discontinued.

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Extra resources for Differential Diagnosis in Surgical Pathology: Expert Consult - Online and Print 2nd Edition

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San Diego, CA. FDA-cleared TMA tests are available for the detection of Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycobacterium tuberculosis (APTIMA CT, APTIMA GC, and, AMPLIFIED Mycobacterium tuberculosis Direct Test [MTD] assays, respectively) An FDA-approved TMA qualitative assay for hepatitis C virus (HCV) is also available (VERSANT HCV RNA [distributed by Siemens Healthcare Diagnostics, Deerfield, IL]) — Nucleic acid sequence–based amplification (NASBA) ◆ NASBA is an isothermal amplification technique and can be used for the amplification of a DNA or RNA target.

Vijaya B.

Nonamplification with a particular probe indicates the presence of a mutation, SNP, or deletion; excess amplification demonstrates an amplification event. MLPA tests (none is currently FDA cleared or approved) are available for the diagnosis of a large variety of pathologic conditions, including ◆ Familial cancers: ataxia telangiectasia, BRCA1 and BRCA2 testing, colon polyposis (APC), MLH1/MSH1/MSH2/MSH6/PMS2 testing, Li-Fraumeni syndrome, multiple endocrine neoplasia, neurofibromatosis types 1 and 2, Peutz-Jeghers syndrome, retinoblastoma, von Hippel-Lindau syndrome, Wilms tumor ◆ Tumor analyses: melanoma (uveal), mismatch repair genes, neuroblastoma, oligodendroma, phosphatase and tensin homologue (PTEN), rhabdoid tumors, tumor suppressor genes ◆ Prenatal and postnatal screening: aneuploidy (Down, Edwards, Patau syndromes), mental retardation syndromes, microdeletion syndromes (Prader-Willi and Angelman syndromes; RETT/Xq28 duplication, and others) ◆ Pharmacogenetics: dihydropyrimidine dehydrogenase (DPD) deficiency ◆ Specific syndromes: cystic fibrosis, Turner and Klinefelter syndromes, typical uremic syndrome, and Wilson disease ● Hybrid capture — The hybrid capture assay (QIAGEN, Germantown, MD) involves an in vitro solution hybridization of a target DNA sequence with an RNA probe, followed by a signal amplification step — Applications: the FDA-approved Digene HPV Test uses hybrid capture (hc2) technology.

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