By Neuroscience Education Institute
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Additional resources for Diagnosis and Treatment of Sleep Wake Disorders
Newer antidepressants may not be as efﬁcacious as TCAs, but may be more tolerable. Although nearly all patients with narcolepsy will require pharmacologic intervention, behavioral management is nonetheless an important part of treatment. It is particularly important for narcolepsy patients to practice good sleep hygiene. These patients should avoid work or lifestyle situations that can cause sleep deprivation or dysregulation, such as shift work, and should not work in hazardous situations. Patients with narcolepsy may beneﬁt from taking brief naps at speciﬁed times, which could require coordination with their employers.
Circle the correct answer) Answer Sheet 1. A B 2. A B 3. A B C 4. A B C 5. B C A C D D 6. E A B 7. A B C D 8. A B C D 9. A B C D D Activity Evaluation: Please rate the following, using a scale of: 1-poor 2-fair 3-good 4-very good 5-excellent 1. The overall quality of the content was… 1 2 3 4 5 2. The relevance of the content to my professional needs was… 1 2 3 4 5 3. The level at which the learning objective was met of teaching me to recognize underlying causes of sleep/wake disorders 1 2 3 4 5 4.
This is thought to reﬂect the activation of GHB receptors at low dose and the GABAB receptors—for which sodium oxybate has only weak afﬁnity—at higher doses. Sodium oxybate can induce sleep without radically changing the natural sleep pattern and was previously used in general anesthesia. It can consolidate disrupted sleep in people with narcolepsy and also improves the occurrence of cataplexy and other daytime symptoms, however the precise mechanism that is operating to help reduce cataplexy is not fully understood.