Diagnosis and Management of Pituitary Disorders by Andrea Lania MD, PHD (auth.), Brooke Swearingen MD, Beverly

By Andrea Lania MD, PHD (auth.), Brooke Swearingen MD, Beverly M. K. Biller MD (eds.)

This textual content offers a close replace on present diagnostic and healing thoughts helpful within the administration of a extensive spectrum of pituitary issues. The contents mirror the multidisciplinary method wanted for sufferers with issues of the pituitary gland, with contributions from either endocrinologists and neurosurgeons, in addition to strong point contributions from radiologists, ophthalmologists, pathologists, radiation oncologists, and neurologists. The e-book specializes in every one pituitary tumor subtype, and comprises extra chapters relating to different lesions of the sella, together with tumor administration while pregnant and within the pediatric age group.

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The WHO definition includes pure GH-producing tumors, mammosomatotroph adenomas, and acidophil stem cell adenomas. Morphologically, the majority of these tumors are macroadenomas and frequently have suprasellar growth and expansion to the lateral sellar wall. Subtype variants include densely granulated somatotroph adenomas and sparsely granulated somatotroph adenomas. Fortunately, they can be distinguished without electron microscopy, since there is a strong correlation between the cytokeratin pattern and the tumor type.

Gejman R, Swearingen B, Hedley-Whyte ET. Role of Ki67 proliferation index and p53 expression in predicting progression of pituitary adenomas Brain Pathol 2006;16(s1):S110. 12. Hsu DW, Hakim F, Biller BM, et al. Significance of proliferating cell nuclear antigen index in predicting pituitary adenoma recurrence. J Neurosurg 1993;78:753–61. 13. Yamada S, Aiba T, Sano T, et al. Growth hormone-producing pituitary adenomas: correlations between clinical characteristics and morphology. Neurosurgery 1993;33:20–7.

The cavernous segment of the internal carotid artery occupies the inferomedial aspect of the cavernous sinus. Cranial Imaging of Pituitary Gland, Sella, Parasellar Region 49 nerve VI (abducens nerve) lies at the inferolateral aspect of the cavernous carotid artery. At the posterior aspect of the cavernous sinus, near the petrous apex, lies Dorello’s canal, through which cranial nerve VI passes before entering the cavernous sinus. Just superior to this is Meckel’s cave, which contains the Gasserian cistern and the trigeminal ganglion.

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