CNS regeneration: basic science and clinical advances by Jeffrey Kordower, Mark H. Tuszynski

By Jeffrey Kordower, Mark H. Tuszynski

This moment variation updates the burgeoning box of regeneration within the important apprehensive procedure (CNS) from molecular, platforms, and disease-based standpoint. whereas the e-book covers a number of parts intimately, specified emphasis is given to discussions of flow issues comparable to Parkinsons affliction, Alzheimers illness, and spinal wire harm. * accommodates info received from state-of-the-art photomicroscopy techniques Read more...

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EMBO J 20: 4332--4336. Caroni P, Aigner L, and Schneider C (1997). Intrinsic neuronal determinants locally regulate extrasynaptic and synaptic growth at the adult neuromuscular junction. J Cell Biol 136: 679-692. Carpenter P, Sefton AJ, Dreher B et al. (1986). Role of target tissue in regulating the development of retinal ganglion cells in the albino rat: effects of kainate lesions in the superior colliculus. J Comp Neurol 251: 240-259. Carter DA, Bray GM, and Aguayo AJ (1989). Regenerated retinal ganglion cell axons can form well-differentiated synapses in the superior colliculus of adult hamsters.

1999). Apoptotic versus necrotic characteristics of retinal ganglion cell death after partial optic nerve injury. J Neurotrauma 16: 153-163. Bilak MM, Shifrin DA, Corse AM et al. (1999). Neuroprotective utility and neurotrophic action of neurturin in postnatal motor neurons: comparison with GDNF and persephin. Mol Cell Neurosci 13: 326-336. Bisby MA and Pollock B (1983). Increased regeneration rate in peripheral nerve axons following double lesions: enhancement of the conditioning lesion phenomenon.

Neuron 15: 805-819. INTRINSIC DETERMINANTS OF AXON REGENERATION 35 Meyer-Franke A, Wilkinson GA, Kruttgen A et al. (1998). Depolarization and cAMP elevation rapidly recruit TrkB to the plasma membrane of CNS neurons. Neuron 21:681-693. Miao T, Wu D, Zhang Y et al. (2006). Suppressor of cytokine signaling-3 suppresses the ability of activated signal transducer and activator of transcription-3 to stimulate neurite growth in rat primary sensory neurons. J Neurosci 26: 9512-9519. Mills CD, Allchorne AJ, Griffin Robert Set al.

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