Applying pharmacogenomics in therapeutics by Xiaodong Feng, Hong-Guang Xie

By Xiaodong Feng, Hong-Guang Xie

Recent advances in high-throughput gene sequencing and different omics biotechnologies have served as a springboard for the sphere of pharmacogenomics. Pharmacogenomics is now mostly authorized because the significant determinant of variable drug safeguard, efficacy, and cost-effectiveness. consequently, frequent use of pharmacogenomics for sufferer care has turn into a severe requirement. there's an exceptional urgency for aspiring and training clinicians to turn into knowledgeable on how one can interpret information from pharmacogenomic checking out in instruction for the way forward for healthcare―i.e., custom-made medicine.

Applying Pharmacogenomics in Therapeutics presents well timed insurance of the foundations, perform, and strength of pharmacogenomics and custom-made drugs. made out of chapters contributed by way of well-established pharmacologists and scientists from US and chinese language academia and undefined, this authoritative text:

  • Demonstrates tips to follow the foundations of pharmacogenomics and its biotechnologies in sufferer care
  • Depicts using genetic biomarkers in drug discovery and improvement, laboratory medication, and scientific services
  • Describes the perform of pharmacogenomics within the remedy of cancers, cardiovascular ailments, neurologic and psychiatric problems, and pulmonary diseases
  • Discusses the merging of pharmacogenomics and replacement medication, in addition to the mixing of pharmacogenomics into pharmacoeconomics

Each bankruptcy starts off with the major innovations, by way of in-depth explorations of case studies or serious reviews of genetic variants/biomarkers, and concludes with questions for self-examination.

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Et al. Cost-effectiveness of using pharmacogenetic information in warfarin dosing for patients with nonvalvular atrial fibrillation. Ann Intern Med, 2009; 150(2): 73–83. National Coalition for Health Professional Education in Genetics. Core Competencies for All Health Care Professionals. 2007. option=com_content&view=article&id=237&Itemid=84 (accessed March 12, 2014). 150. , et al. Pharmacogenomics: A scientific revolution in pharmaceutical sciences and pharmacy practice. Report of the 2001–2002 Academic Affairs Committee.

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